Investigating the effects of plastic chemicals on blood transfusion safety.
Does biocompatibility contribute to transfusion-related adverse effects?
This study is looking into how chemicals from plastic medical products might affect kids during blood transfusions, especially after heart surgery, to help identify any risks and keep patients safe.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Research Institute NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project ID | NIH-11049888 on NIH RePORTER |
What this research studies
This research explores how exposure to chemicals from plastic medical products may lead to adverse effects during blood transfusions, particularly in pediatric patients. The study will utilize both animal models and human data to understand the mechanisms by which these chemicals can affect heart function and blood quality. By examining the relationship between plastic chemical exposure and postoperative complications in cardiac surgery patients, the research aims to identify potential risks associated with common medical practices. Patients may be monitored for changes in their health related to these exposures.
Who could benefit from this research
Good fit: Ideal candidates for this research include pediatric patients undergoing cardiac surgery who may be exposed to plastic medical products.
Not a fit: Patients who are not undergoing surgical procedures or who do not require blood transfusions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved safety protocols for blood transfusions and better health outcomes for patients exposed to plastic chemicals.
How similar studies have performed: Previous studies have indicated concerning associations between plastic chemical exposure and health risks, suggesting that this research addresses a significant and potentially novel area of inquiry.
Where this research is happening
Washington, United States
- Children's Research Institute — Washington, United States (Active)
Researchers
- Principal investigator: Posnack, Nikki Gillum — Children's Research Institute
- Study coordinator: Posnack, Nikki Gillum
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.