Investigating the effects of opioid use during pregnancy on fetal and placental health

Multimodal Fetal and Placental Imaging and Biomarkers of Clinical Outcomes in Opioid Use Disorder

NIH-funded research Indiana University Indianapolis · NIH-10750306

This study is looking at how using opioids during pregnancy can impact the health of both the baby and the placenta, using special imaging and tests to find early signs of any problems, so we can help moms and their little ones stay healthier.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIndiana University Indianapolis NIH-funded
Lab location1 site (Indianapolis, United States)
Project IDNIH-10750306 on NIH RePORTER

What this research studies

This research focuses on understanding how maternal opioid use disorder affects fetal and placental health through advanced imaging techniques and biomarkers. It aims to identify early predictors of adverse outcomes for both mothers and infants exposed to opioids during pregnancy. By utilizing longitudinal and serial imaging, the study will assess changes in placental morphology and fetal development, providing insights into the risks associated with prenatal opioid exposure. The findings could lead to better management strategies for pregnant women with opioid use disorder and their infants.

Who could benefit from this research

Good fit: Ideal candidates for participation include pregnant women with a history of opioid use disorder and their infants.

Not a fit: Patients who are not pregnant or those without any history of opioid use may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prediction and management of health outcomes for mothers and infants affected by opioid use during pregnancy.

How similar studies have performed: Previous studies have shown promising results in understanding the impacts of prenatal opioid exposure, indicating that this research builds on established findings.

Where this research is happening

Indianapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.