Investigating the effects of mitochondria on aging in people with HIV

Collaboration on HIV and AgingResearch through the Study of Mitochondria

NIH-funded research Johns Hopkins University · NIH-10896295

This study is looking at how damage to tiny parts of your cells called mitochondria affects aging in people living with HIV, and it will also see how exercise can help improve health as you age with the condition.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10896295 on NIH RePORTER

What this research studies

This research focuses on understanding how mitochondrial damage affects aging in individuals living with HIV. The principal investigator, Dr. Jing Sun, will analyze data from long-term HIV cohorts to explore the relationship between mitochondrial DNA and biological aging. The study will also assess how exercise impacts mitochondrial function and aging-related health outcomes in people with HIV. By bridging the fields of HIV epidemiology, genetics, and aging, this research aims to improve long-term health for those affected by HIV.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 21 and older who are living with HIV.

Not a fit: Patients who are not living with HIV or are under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes and quality of life for individuals living with HIV as they age.

How similar studies have performed: Previous research has shown promising results in understanding the relationship between mitochondrial function and aging, suggesting that this approach could yield valuable insights.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.