Investigating the effects of mild traumatic brain injury in children
Official title: Pediatric Mild Traumatic Brain Injury and the ABCD Study: A Prospective Behavioral, Psychiatric, Neurocognitive, Imaging, and Genetic Investigation
Funded at University of California, San Diego · NIH-11082517 · Data updated 2026-11-12
This study is looking at how mild traumatic brain injuries (like concussions) affect kids aged 0-11, comparing their behavior and thinking skills to other kids who have had different injuries or no injuries at all, to help us understand how these injuries might impact their growth and development.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | June 15, 2022 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $442,724 |
| NIH project number | 5R01HD105338-04 |
| Project ID | NIH-11082517 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who have experienced a mild traumatic brain injury.
✕Less likely to help
Patients who have not experienced any form of injury or those outside the age range of 0-11 years may not benefit from this research.
What this research studies
This research focuses on understanding the impact of mild traumatic brain injury (mTBI) on children aged 0-11 years. By analyzing data from the Adolescent Brain Cognitive Development (ABCD) study, researchers will explore behavioral, psychiatric, and neurocognitive outcomes associated with mTBI. The study will compare children who have experienced mTBI with those who have had other injuries and those with no injuries, using pre- and post-injury data to identify predictive factors. This comprehensive approach aims to uncover the mechanisms behind the effects of mTBI on young children's development.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of behavioral and cognitive issues following mild traumatic brain injuries in children.
How similar studies have gone: Previous research has shown success in understanding the effects of traumatic brain injuries in children, but this specific approach utilizing the ABCD study data is relatively novel.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Max, Jeffrey Edwin — University of California, San Diego
- Study coordinator: Max, Jeffrey Edwin
Related research
Other NIH-funded projects on the same topics.
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Mild Traumatic Brain Injury: A High-Tech Look Inside the Brain with Diffusion MRI
Researchers are using advanced brain imaging to find biological clues in people who have mild traumatic brain injuries.
-
How neuromodulation may help headaches after a mild brain injury
A small study tests whether stimulating the brain with a noninvasive technique can lessen persistent headaches in people who recently had a concussion.
-
New ways to treat chronic pain after mild brain injuries
A research team is studying why some people develop long-lasting pain after a mild head injury and how brain inflammation contributes to it.
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Retraining brain pathways to boost thinking after a mild head injury
A clinical trial tests a brain-training program to improve thinking and memory in people who have had a mild traumatic brain injury (mTBI).
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Neurobehavioral effects of childhood brain injuries and addiction risk in twins
This grant studies how mild traumatic brain injury in childhood might influence behavior and the chance of developing addictive behaviors later in life, using twins to understand what’s due to injury versus other factors.
-
Understanding and improving reactive balance after mild traumatic brain injury
This grant tests how people recover their balance after a mild brain injury and how targeted training could help prevent falls.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.