Investigating the effects of methylmercury and arsenic on zebrafish and their offspring's behavior
Parental Co-Exposure to Methylmercury and Inorganic Arsenic in Zebrafish (Danio rerio): Metabolism and Offspring Behavior
This study is looking at how two harmful chemicals, methylmercury and inorganic arsenic, affect zebrafish and their babies, helping us understand how these substances might impact their growth and behavior, which could also give us clues about risks in our environment.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon State University NIH-funded |
| Lab location | 1 site (Corvallis, United States) |
| Project ID | NIH-10352116 on NIH RePORTER |
What this research studies
This research explores how exposure to methylmercury and inorganic arsenic affects zebrafish and their offspring. The study will examine how these chemicals are absorbed and metabolized in adult zebrafish, and how they impact the behavior and development of their young. By using a model system of zebrafish, researchers aim to uncover the biological mechanisms behind the neurotoxic effects of these substances. The findings could provide insights into the potential risks of chemical mixtures in the environment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals concerned about the effects of environmental toxins, particularly those with a history of exposure to heavy metals.
Not a fit: Patients who have no exposure to methylmercury or inorganic arsenic may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of the neurotoxic effects of environmental contaminants, potentially informing public health policies and safety regulations.
How similar studies have performed: While the investigation of chemical mixtures is a growing field, the specific focus on the combined effects of methylmercury and arsenic in zebrafish is relatively novel.
Where this research is happening
Corvallis, United States
- Oregon State University — Corvallis, United States (Active)
Researchers
- Principal investigator: Rothenberg, Sarah E — Oregon State University
- Study coordinator: Rothenberg, Sarah E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.