Investigating the effects of metals and the microbiome on kidney health in adolescents in Central America
Metals, the Microbiome, and Kidney Health Among Adolescents in Central America
This study is looking at how being around certain metals might affect the kidney health of teenagers in Central America, especially in areas where many people have kidney problems, and it involves collecting samples and health information from over 400 young people to find out more about this connection.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10902384 on NIH RePORTER |
What this research studies
This research focuses on understanding how exposure to metals affects kidney health among adolescents in Central America, particularly in regions with high rates of chronic kidney disease of unknown etiology (CKDu). The study involves collecting biological samples and health surveys from youth to assess their exposure to metals and kidney function. Researchers will analyze the relationship between metal exposure, kidney health, and the urinary microbiome, which may play a crucial role in these processes. By following a cohort of over 400 young participants, the study aims to uncover early indicators of kidney disease linked to environmental factors.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 12 to 20 living in Central America, particularly those in agricultural communities.
Not a fit: Patients outside the age range of 12 to 20 or those not residing in the targeted regions of Central America may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for kidney disease in at-risk youth.
How similar studies have performed: While the specific focus on the microbiome and metals in this context is novel, there is existing research indicating that environmental exposures can significantly impact kidney health.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Hall, Samantha — Boston University Medical Campus
- Study coordinator: Hall, Samantha
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.