Investigating the effects of marine lipid supplements on chronic jaw pain.

Safety and analgesic efficacy of marine lipid precursors of specialized pro-resolving mediators in adults with chronic temporomandibular pain.

NIH-funded research Univ of North Carolina Chapel Hill · NIH-11093724

This study is looking at whether taking a special marine oil can help adults with chronic jaw pain from temporomandibular disorder (TMD) feel better, and it’s designed for people who are dealing with this kind of pain.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-11093724 on NIH RePORTER

What this research studies

This research explores the potential benefits of marine omega-3 fatty acids in alleviating chronic pain associated with temporomandibular disorder (TMD). By conducting a randomized, placebo-controlled trial, the study aims to evaluate the safety and effectiveness of a specific marine oil supplement in reducing pain intensity in adults suffering from TMD. Participants will be monitored for changes in pain levels using a numeric rating scale, and the study will utilize advanced techniques to analyze the biochemical effects of the treatment. The goal is to provide a scientifically rigorous assessment of this novel therapeutic approach.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who experience chronic pain related to temporomandibular disorder.

Not a fit: Patients who do not have chronic temporomandibular disorder or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a new dietary supplement option for patients suffering from chronic jaw pain, potentially improving their quality of life.

How similar studies have performed: Previous research has indicated the potential of omega-3 fatty acids in pain management, but this specific approach is novel and has not been extensively tested in a controlled trial setting.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.