Investigating the effects of lipoprotein(a) on cardiovascular health in diverse populations

Phenotypic consequences of lipoprotein(a) in diverse populations

NIH-funded research Univ of North Carolina Chapel Hill · NIH-11050476

This study is looking at how a substance called lipoprotein(a) affects heart health in people from different ethnic backgrounds, and it's for anyone interested in understanding more about this link and how it might impact their cardiovascular health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-11050476 on NIH RePORTER

What this research studies

This research focuses on understanding how lipoprotein(a), a type of lipoprotein linked to cardiovascular disease, affects individuals from various ethnic backgrounds. By assembling a large and diverse group of participants, the study aims to measure lipoprotein(a) levels and their relationship with cardiovascular health. The research will utilize advanced assays and genetic data to explore the mechanisms behind lipoprotein(a) and its potential adverse effects when treated. This approach seeks to fill gaps in current knowledge, particularly regarding populations that have been underrepresented in previous studies.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals from diverse ethnic backgrounds, particularly those with a family history of cardiovascular disease or elevated lipoprotein(a) levels.

Not a fit: Patients who do not have elevated lipoprotein(a) levels or those with unrelated cardiovascular conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatments for cardiovascular disease based on individual lipoprotein(a) levels.

How similar studies have performed: Previous research has shown promising results in understanding lipoprotein(a) across different populations, but this study aims to expand on that knowledge with a more diverse cohort.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions adult onset diabetesAdult-Onset Diabetes Mellitus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.