Investigating the effects of lipoprotein(a) on cardiovascular health in diverse populations
Official title: Phenotypic consequences of lipoprotein(a) in diverse populations
Funded at Univ of North Carolina Chapel Hill · NIH-11050476 · Data updated 2026-11-12
This study is looking at how a substance called lipoprotein(a) affects heart health in people from different ethnic backgrounds, and it's for anyone interested in understanding more about this link and how it might impact their cardiovascular health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | January 15, 2025 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $1,602,792 |
| NIH project number | 1R01HL172887-01A1 |
| Project ID | NIH-11050476 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals from diverse ethnic backgrounds, particularly those with a family history of cardiovascular disease or elevated lipoprotein(a) levels.
✕Less likely to help
Patients who do not have elevated lipoprotein(a) levels or those with unrelated cardiovascular conditions may not benefit from this research.
What this research studies
This research focuses on understanding how lipoprotein(a), a type of lipoprotein linked to cardiovascular disease, affects individuals from various ethnic backgrounds. By assembling a large and diverse group of participants, the study aims to measure lipoprotein(a) levels and their relationship with cardiovascular health. The research will utilize advanced assays and genetic data to explore the mechanisms behind lipoprotein(a) and its potential adverse effects when treated. This approach seeks to fill gaps in current knowledge, particularly regarding populations that have been underrepresented in previous studies.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for cardiovascular disease based on individual lipoprotein(a) levels.
How similar studies have gone: Previous research has shown promising results in understanding lipoprotein(a) across different populations, but this study aims to expand on that knowledge with a more diverse cohort.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Avery, Christy Leigh — Univ of North Carolina Chapel Hill
- Study coordinator: Avery, Christy Leigh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.