NIH-funded research NIH-funded research

Investigating the effects of ingested nanoplastics on health using a model organism

Official title: A whole animal model for investigation of ingested nanoplastic mixtures and effects on genomic integrity and health

Funded at St. Mary's University · NIH-10907635 · Data updated 2026-11-12

This study is looking at how tiny plastic particles, called nanoplastics, might harm our health by carrying harmful chemicals into our bodies, using a small worm called C. elegans to help understand the risks, especially since these plastics are showing up in human tissues.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionSt. Mary's University
NIH-funded
Lab location1 site (San Antonio, United States)
Project startSeptember 1, 2023
Project endJuly 31, 2027
Funding year2024
Award (this year)$168,750
NIH project number5R16GM150406-02
Project IDNIH-10907635 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals concerned about the health impacts of environmental pollutants and microplastics.

Less likely to help

Patients who are not exposed to environmental pollutants or microplastics may not receive direct benefits from this research.

What this research studies

This research focuses on understanding how nanoplastics, tiny plastic particles, affect health by using a model organism called Caenorhabditis elegans (C. elegans). The study aims to explore how these nanoplastics can carry harmful environmental chemicals into biological systems and potentially cause DNA damage. By examining the interactions between nanoplastics and chemicals, researchers hope to uncover the risks associated with their ingestion. This work is crucial as microplastics are increasingly found in human tissues and may pose significant health risks.

Why it matters

Potential benefit: If successful, this research could lead to a better understanding of the health risks posed by nanoplastics and inform public health policies regarding plastic consumption.

How similar studies have gone: While research on microplastics is emerging, this specific approach using C. elegans as a model for studying the effects of nanoplastics and chemical mixtures is relatively novel.

Where this research is happening

  • St. Mary's University
    San Antonio, United States
    Active

Researchers

  • Principal investigator: Harr, Jennifer — St. Mary's University
  • Study coordinator: Harr, Jennifer

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.