Investigating the effects of harmful chemicals on zebrafish development
Developmental VOC Exposure in Zebrafish: Toxic Mechanisms and Biomarkers
This study is looking at how common air pollutants called volatile organic compounds (VOCs) affect the health and development of zebrafish, which can help us understand the risks these chemicals might pose to both fish and people, especially in cities.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wayne State University NIH-funded |
| Lab location | 1 site (Detroit, United States) |
| Project ID | NIH-10867386 on NIH RePORTER |
What this research studies
This research focuses on understanding how exposure to volatile organic compounds (VOCs), which are common environmental pollutants, affects the development and health of zebrafish. By using zebrafish as a model organism, the study aims to identify the toxic mechanisms and potential biomarkers associated with VOC exposure. The research will employ innovative techniques to assess the impact of these chemicals on various biological systems, including immune and reproductive health. The findings could provide insights into the health risks posed by VOCs to both aquatic life and humans, particularly in urban areas.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living in urban areas who may be exposed to VOCs, particularly pregnant women and families with young children.
Not a fit: Patients who do not live in urban environments or who have no known exposure to VOCs may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention of health issues related to environmental pollutants in humans.
How similar studies have performed: Previous research has shown that studying environmental contaminants in model organisms like zebrafish can yield valuable insights into human health risks, indicating a promising approach.
Where this research is happening
Detroit, United States
- Wayne State University — Detroit, United States (Active)
Researchers
- Principal investigator: Baker, Tracie R — Wayne State University
- Study coordinator: Baker, Tracie R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.