Investigating the effects of fructose on diabetes and metabolism
Official title: Fructose: Substrate, Stimulus, or Both?
Funded at Touro University of California · NIH-10553588 · Data updated 2026-11-12
This study is looking at how eating fructose, a type of sugar found in many foods, affects blood sugar and fat production, especially for people with type 2 diabetes, to help create better dietary advice for managing their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Touro University of California NIH-funded |
| Lab location | 1 site (Vallejo, United States) |
| Project start | January 1, 2019 |
| Project end | December 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $714,999 |
| NIH project number | 5R01DK116033-04 |
| Project ID | NIH-10553588 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include individuals aged 0-21 and adults with type 2 diabetes or those at risk of developing it.
✕Less likely to help
Patients who do not consume fructose or have other unrelated metabolic disorders may not benefit from this research.
What this research studies
This research explores how fructose consumption affects blood sugar levels and fat production in the body, particularly in relation to type 2 diabetes. By examining the mechanisms of fructose metabolism, the study aims to clarify whether fructose directly contributes to fat synthesis or indirectly influences blood sugar levels through other metabolic pathways. Participants may undergo dietary assessments and metabolic testing to understand how fructose impacts their health. The findings could lead to more effective dietary recommendations for managing diabetes.
Why it matters
Potential benefit: If successful, this research could provide clearer dietary guidelines for individuals at risk of or living with type 2 diabetes.
How similar studies have gone: Previous research has indicated a link between fructose consumption and metabolic disorders, but this specific approach to understanding its mechanisms is relatively novel.
Where this research is happening
-
Touro University of California
Vallejo, United States Active
Researchers
- Principal investigator: Schwarz, Jean-Marc — Touro University of California
- Study coordinator: Schwarz, Jean-Marc
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.