Investigating the effects of fluoride exposure on brain development in children
Fluoride in Tooth Dentin and Neurodevelopmental Outcome in a Canadian Cohort
This study is looking at how fluoride exposure during important growth stages might impact kids' brain health and thinking skills by checking the fluoride levels in baby teeth from 800 children and seeing how it relates to their IQ and attention issues, so we can better understand any risks of fluoride for young kids.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | York University NIH-funded |
| Lab location | 1 site (Toronto, Canada) |
| Project ID | NIH-10848505 on NIH RePORTER |
What this research studies
This research examines how fluoride exposure during critical developmental periods affects children's brain health and cognitive abilities. By analyzing shed baby teeth from 800 children, the study aims to quantify fluoride levels and their timing, linking these to IQ scores and attention problems. The research utilizes advanced techniques to measure fluoride and toxic metals in tooth dentin, providing a historical record of exposure. The findings could help clarify the potential risks associated with fluoride consumption in early life.
Who could benefit from this research
Good fit: Ideal candidates for this research include children aged 0-11 years, particularly those who have had their baby teeth shed.
Not a fit: Patients who are not children or those who have not been exposed to fluoride during critical developmental periods may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and guidelines regarding fluoride exposure and its impact on children's cognitive development.
How similar studies have performed: Previous studies have raised concerns about fluoride exposure, but this research is innovative in its approach to measuring historical exposure through tooth dentin.
Where this research is happening
Toronto, Canada
- York University — Toronto, Canada (Active)
Researchers
- Principal investigator: Till, Christine — York University
- Study coordinator: Till, Christine
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.