Investigating the effects of fermented wheat germ proteins on cancer treatment
Official title: Fermented wheat germ proteins;mechanistic, immunologic and pre-clinical canine studies
Funded at VA Northern California Health Care Sys · NIH-10946716 · Data updated 2026-11-12
This study is looking at how fermented wheat germ extract (FWGE) might help improve cancer treatment by seeing how it works with cancer cells and the immune system, and it could offer new options for patients who are exploring ways to boost their traditional therapies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA Northern California Health Care Sys NIH-funded |
| Lab location | 1 site (Mather, United States) |
| Project start | October 1, 2019 |
| Project end | September 30, 2025 |
| Funding year | 2025 |
| NIH project number | 5I01BX004669-06 |
| Project ID | NIH-10946716 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults diagnosed with cancer who are interested in exploring complementary treatment options.
✕Less likely to help
Patients who are not diagnosed with cancer or those who do not wish to explore complementary therapies may not benefit from this research.
What this research studies
This research explores the potential benefits of fermented wheat germ extract (FWGE) as a complementary treatment for cancer. It focuses on understanding how FWGE interacts with cancer cells and the immune system, using both laboratory studies and pre-clinical trials in canine models. The goal is to gather rigorous evidence on the efficacy and mechanisms of FWGE, which is already available as a dietary supplement. Patients may benefit from insights into new treatment options that could enhance traditional cancer therapies.
Why it matters
Potential benefit: If successful, this research could provide new insights into effective complementary therapies for cancer treatment.
How similar studies have gone: While some preliminary studies have shown promise for similar approaches, this research aims to provide more rigorous evidence and is considered a novel investigation.
Where this research is happening
-
VA Northern California Health Care Sys
Mather, United States Active
Researchers
- Principal investigator: Tuscano, Joseph M — VA Northern California Health Care Sys
- Study coordinator: Tuscano, Joseph M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.