Investigating the effects of different light wavelengths on dental materials and inflammation

Temperature changes and inflammatory response in pulpal and gingival tissues surrounding dental restorative treatments performed using blue and red wavelengths: an in vivo and ex vivo study

NIH-funded research University of Florida · NIH-11032477

This study is looking at how different colors of light used in dental treatments can affect inflammation in your mouth, with the hope of finding safer ways to help your teeth heal while keeping any discomfort to a minimum.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Florida NIH-funded
Lab location1 site (Gainesville, United States)
Project IDNIH-11032477 on NIH RePORTER

What this research studies

This research focuses on how different light wavelengths, specifically blue and red light, affect the inflammatory response in dental tissues during restorative treatments. By examining both in vivo and ex vivo conditions, the study aims to understand the potential risks associated with blue light, such as tissue damage and inflammation, while exploring the benefits of using red light, which may reduce inflammation and promote healing. Patients may be involved in trials assessing the safety and effectiveness of these light-cured dental materials. The goal is to develop safer dental treatments that minimize adverse effects on oral tissues.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals undergoing dental restorative treatments who may be at risk for inflammation or tissue damage.

Not a fit: Patients who do not require dental restorative treatments or have contraindications for light exposure may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer dental restorative procedures with reduced inflammation and improved healing for patients.

How similar studies have performed: Previous research has indicated that using longer wavelengths of light can reduce inflammation and improve cellular function, suggesting a promising avenue for further exploration.

Where this research is happening

Gainesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.