Investigating the effects of different light wavelengths on dental materials and inflammation
Official title: Temperature changes and inflammatory response in pulpal and gingival tissues surrounding dental restorative treatments performed using blue and red wavelengths: an in vivo and ex vivo study
Funded at University of Florida · NIH-11032477 · Data updated 2026-11-12
This study is looking at how different colors of light used in dental treatments can affect inflammation in your mouth, with the hope of finding safer ways to help your teeth heal while keeping any discomfort to a minimum.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | September 16, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $156,060 |
| NIH project number | 1K23DE034470-01 |
| Project ID | NIH-11032477 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals undergoing dental restorative treatments who may be at risk for inflammation or tissue damage.
✕Less likely to help
Patients who do not require dental restorative treatments or have contraindications for light exposure may not benefit from this research.
What this research studies
This research focuses on how different light wavelengths, specifically blue and red light, affect the inflammatory response in dental tissues during restorative treatments. By examining both in vivo and ex vivo conditions, the study aims to understand the potential risks associated with blue light, such as tissue damage and inflammation, while exploring the benefits of using red light, which may reduce inflammation and promote healing. Patients may be involved in trials assessing the safety and effectiveness of these light-cured dental materials. The goal is to develop safer dental treatments that minimize adverse effects on oral tissues.
Why it matters
Potential benefit: If successful, this research could lead to safer dental restorative procedures with reduced inflammation and improved healing for patients.
How similar studies have gone: Previous research has indicated that using longer wavelengths of light can reduce inflammation and improve cellular function, suggesting a promising avenue for further exploration.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Oliveira, Dayane — University of Florida
- Study coordinator: Oliveira, Dayane
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.