Investigating the effects of deltamethrin on brain development and behavior.
Neurotoxicology of deltamethrin in the developing brain
['FUNDING_R01'] · UNIVERSITY OF TEXAS MED BR GALVESTON · NIH-10868462
This study is looking at how being around the pesticide deltamethrin when young might affect brain development and lead to issues like ADHD, helping us understand how it could impact attention and behavior.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS MED BR GALVESTON (nih funded) |
| Locations | 1 site (GALVESTON, UNITED STATES) |
| Trial ID | NIH-10868462 on ClinicalTrials.gov |
What this research studies
This research examines how exposure to the pesticide deltamethrin during early life may contribute to neurodevelopmental disorders such as ADHD. By using animal models, the study aims to understand the mechanisms by which deltamethrin disrupts brain function, particularly focusing on dopamine signaling and the activity of specific brain cells that regulate behavior. The research will explore the impact of deltamethrin on brain regions associated with attention and impulse control, providing insights into potential risks from environmental exposures.
Who could benefit from this research
Good fit: Ideal candidates for this research are children who have been exposed to pyrethroid pesticides and exhibit symptoms of ADHD or other neurodevelopmental issues.
Not a fit: Patients who have not been exposed to pyrethroid pesticides or do not exhibit neurodevelopmental disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention strategies for ADHD and other neurodevelopmental disorders linked to environmental toxins.
How similar studies have performed: Previous research has indicated a link between pesticide exposure and ADHD, suggesting that this study builds on established findings but explores new mechanisms.
Where this research is happening
GALVESTON, UNITED STATES
- UNIVERSITY OF TEXAS MED BR GALVESTON — GALVESTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LAEZZA, FERNANDA — UNIVERSITY OF TEXAS MED BR GALVESTON
- Study coordinator: LAEZZA, FERNANDA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.