Investigating the effects of chemotherapy on brain function in young cancer survivors

MRI study of chemobrain in pediatric oncology patients

['FUNDING_R01'] · ALBERT EINSTEIN COLLEGE OF MEDICINE · NIH-10860981

This study is looking at how chemotherapy affects the thinking and social skills of kids who have survived cancer, using special brain scans to see what changes happen over time, so we can find better ways to help them.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorALBERT EINSTEIN COLLEGE OF MEDICINE (nih funded)
Locations1 site (BRONX, UNITED STATES)
Trial IDNIH-10860981 on ClinicalTrials.gov

What this research studies

This research focuses on understanding the cognitive and psychosocial challenges faced by pediatric cancer survivors who have undergone chemotherapy, a condition often referred to as 'chemobrain.' By utilizing advanced MRI techniques, the study aims to identify and evaluate the brain changes associated with chemotherapy, including cognitive function, brain connectivity, and structural integrity. The research will track these changes over time to better understand how chemotherapy impacts brain development during critical growth years. This knowledge is essential for developing targeted interventions to support affected children.

Who could benefit from this research

Good fit: Ideal candidates for this research are pediatric cancer survivors who have received chemotherapy and are experiencing cognitive or psychosocial difficulties.

Not a fit: Patients who have not undergone chemotherapy or those without any cognitive or psychosocial challenges may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for identifying and mitigating cognitive deficits in children who have undergone chemotherapy.

How similar studies have performed: Previous research has shown promising results in understanding chemobrain effects in adults, but this specific approach in pediatric patients is relatively novel.

Where this research is happening

BRONX, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.