Investigating the effects of cannabis on inflammation and brain health in people with HIV
Cannabis, inflammation, and the brain in persons with HIV
This study is looking at how cannabis might help reduce inflammation in people living with HIV who are on treatment, and it’s for anyone interested in understanding how cannabis could improve health and brain function in this group.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10863969 on NIH RePORTER |
What this research studies
This research explores how cannabis may help reduce chronic inflammation in individuals living with HIV who are on antiretroviral therapy. It aims to understand the relationship between cannabis use and inflammation-related neuropsychiatric and cognitive issues. The study will involve 120 participants, including those with HIV and healthy individuals, to assess the impact of cannabis on inflammation and its potential therapeutic benefits. By examining various doses and frequencies of cannabis use, the research seeks to fill knowledge gaps regarding its safety and effectiveness.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are currently on suppressive antiretroviral therapy and may be using or considering cannabis for symptom management.
Not a fit: Patients who are not living with HIV or those who are not on antiretroviral therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for managing inflammation and improving mental health outcomes in people with HIV.
How similar studies have performed: While cannabis has shown clinical benefits for various conditions, research specifically examining its effects on inflammation in HIV is still emerging and largely untested.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Iudicello, Jennifer E — University of California, San Diego
- Study coordinator: Iudicello, Jennifer E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.