Investigating the effects of cannabis compounds on behavior and cognition

Rocky Mountain Cannabis Research Center

['FUNDING_OTHER'] · UNIVERSITY OF COLORADO DENVER · NIH-10912672

This study is looking at how CBD might change the way THC affects thinking and behavior in people of different ages, and it’s for anyone interested in understanding how these substances work together.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF COLORADO DENVER (nih funded)
Locations1 site (Aurora, UNITED STATES)
Trial IDNIH-10912672 on ClinicalTrials.gov

What this research studies

This research focuses on understanding how cannabidiol (CBD) influences the effects of tetrahydrocannabinol (THC) on behavior and cognition in individuals of various age groups. By utilizing mobile laboratories, researchers will collect biological samples to assess the immediate impacts of THC and CBD on neurocognitive functions and behavioral outcomes. Participants will be randomly assigned to receive either CBD or a placebo, allowing for a controlled examination of how different doses and formulations of CBD affect THC's effects. The study aims to uncover the underlying mechanisms involving the endocannabinoid system and associated lipids.

Who could benefit from this research

Good fit: Ideal candidates include adults and adolescents aged 12 and older who are interested in the effects of cannabis on behavior and cognition.

Not a fit: Patients who do not use cannabis or have contraindications to its use may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved therapeutic strategies for managing the effects of cannabis in various populations.

How similar studies have performed: Previous research has shown promising results in understanding the interactions between CBD and THC, suggesting that this approach could yield valuable insights.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.