Investigating the effects of cannabidiol on cannabis concentrate users

Cannabidiol and Cannabis Concentrate Users: A Randomized, Placebo Controlled Study

NIH-funded research University of Colorado Denver · NIH-10912687

This study is looking at how CBD might help people who often use strong cannabis products, and if you join, you'll try either CBD or a placebo for four weeks while using your usual cannabis, to see how it affects your experience and cravings.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project IDNIH-10912687 on NIH RePORTER

What this research studies

This research explores how cannabidiol (CBD) can impact individuals who frequently use high-THC cannabis concentrates. Participants will be recruited to take part in a four-week program where they will receive either CBD or a placebo while using cannabis concentrates. The study aims to assess the effects of CBD on cannabis use, subjective experiences, and cravings, utilizing a mobile pharmacology lab for data collection. By understanding the therapeutic potential of CBD, the research seeks to identify ways to mitigate the risks associated with high-THC products.

Who could benefit from this research

Good fit: Ideal candidates are adults aged 21 and older who are frequent users of cannabis concentrates.

Not a fit: Patients who do not use cannabis or who are not interested in cannabis products may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could help reduce the negative effects of high-THC cannabis use and improve overall well-being for users.

How similar studies have performed: Previous studies have shown promising results regarding the effects of CBD on THC-related outcomes, indicating that this approach has potential for success.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.