Investigating the effects of caloric restriction and time-restricted feeding on health in older adults
Health Aging & Later-Life Outcomes - pilot (HALLO-P)
This study is looking at how eating less food and timing meals can help older adults stay healthier and reduce the risk of diseases, and it’s for people aged 60 and up who want to explore these dietary changes.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project ID | NIH-11146215 on NIH RePORTER |
What this research studies
The Health, Aging and Later-Life Outcomes Planning Grant (HALLO-P) aims to explore how caloric restriction and time-restricted feeding can impact health outcomes in older adults. This research will involve a pilot study with 120 participants aged 60 and older, focusing on the feasibility of these dietary interventions and their effects on disease and disability risk. Participants will be randomly assigned to different dietary regimens, and innovative mobile health tools will be used to help them adhere to the protocols. The ultimate goal is to design a larger clinical trial that can definitively assess the benefits of these dietary approaches.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 60 and above, particularly those with a BMI of 27 kg/m2 or higher.
Not a fit: Patients who are younger than 60 years or have a BMI below 27 kg/m2 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to effective dietary strategies that improve health and reduce disease risk in older adults.
How similar studies have performed: Previous clinical trials on caloric restriction have shown promising results, indicating that this approach may be beneficial, but the specific application of time-restricted feeding in this context is relatively novel.
Where this research is happening
Winston-Salem, United States
- Wake Forest University Health Sciences — Winston-Salem, United States (Active)
Researchers
- Principal investigator: Kritchevsky, Stephen B. — Wake Forest University Health Sciences
- Study coordinator: Kritchevsky, Stephen B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.