Investigating the effects of caloric restriction and time-restricted feeding on health in older adults
Health Aging & Later-Life Outcomes Planning (HALLO-P)
The HALLO-P project is looking at how eating less food or eating only during certain hours can affect the health of older adults, and it will involve a friendly study where some participants will try these diets while others won’t, all with the help of handy mobile tools to keep everyone on track.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project ID | NIH-10906442 on NIH RePORTER |
What this research studies
The Health Aging & Later-Life Outcomes Planning (HALLO-P) project aims to explore how caloric restriction (CR) and time-restricted feeding (TRF) can impact health outcomes in older adults. This research will involve a multi-site, randomized clinical trial comparing the health effects of CR, TRF, and a control group that does not follow a dietary regimen. The study will utilize mobile health tools to help participants adhere to their assigned diets. A pilot study will enroll 120 older adults to assess the feasibility and effectiveness of these dietary interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 60 years and above, particularly those with a BMI of 27 kg/m2 or higher.
Not a fit: Patients who are younger than 60 years or have a BMI below 27 kg/m2 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved dietary strategies that enhance health and reduce disease risk in older adults.
How similar studies have performed: Previous clinical trials have shown promising results with caloric restriction, but this specific approach comparing CR and TRF in older adults is relatively novel.
Where this research is happening
Winston-Salem, United States
- Wake Forest University Health Sciences — Winston-Salem, United States (Active)
Researchers
- Principal investigator: Kritchevsky, Stephen B. — Wake Forest University Health Sciences
- Study coordinator: Kritchevsky, Stephen B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.