Investigating the effects of caloric restriction and time-restricted feeding on health in older adults
NCI Administrative Supplement for the HALLO-P Planning Project
['FUNDING_U01'] · WAKE FOREST UNIVERSITY HEALTH SCIENCES · NIH-10844298
This study is looking at how eating less food or only during certain hours can affect the health of older adults, and it will help set up a bigger trial to see which method works better for reducing health risks, using handy mobile tools to support participants along the way.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WAKE FOREST UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (WINSTON-SALEM, UNITED STATES) |
| Trial ID | NIH-10844298 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how caloric restriction (CR) and time-restricted feeding (TRF) can impact health outcomes in older adults. The project aims to develop a protocol for a large clinical trial that will compare the effects of these dietary approaches on disease and disability risk. By enrolling older adults, the study will utilize innovative mobile health tools to help participants adhere to their assigned dietary regimens. A pilot study will be conducted to gather essential data on feasibility and effectiveness before launching the full-scale trial.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 60 years and above, particularly those with a BMI of 27 kg/m2 or higher.
Not a fit: Patients who are younger than 60 years or have a BMI below 27 kg/m2 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved dietary strategies that enhance health and reduce disease risk in older adults.
How similar studies have performed: Previous studies on caloric restriction have shown beneficial physiological changes, but this specific approach comparing CR and TRF in older adults is novel.
Where this research is happening
WINSTON-SALEM, UNITED STATES
- WAKE FOREST UNIVERSITY HEALTH SCIENCES — WINSTON-SALEM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KRITCHEVSKY, STEPHEN B. — WAKE FOREST UNIVERSITY HEALTH SCIENCES
- Study coordinator: KRITCHEVSKY, STEPHEN B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.