Investigating the effects of caloric restriction and time-restricted feeding on health in older adults

Health Aging & Later-Life Outcomes Planning (HALLO-P)

['FUNDING_U01'] · WAKE FOREST UNIVERSITY HEALTH SCIENCES · NIH-10674850

This study is looking at how eating less and timing your meals might help older adults stay healthier, and it's inviting people aged 60 and up to join in and see if these eating habits can lower the chances of getting sick or facing disabilities.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorWAKE FOREST UNIVERSITY HEALTH SCIENCES (nih funded)
Locations1 site (WINSTON-SALEM, UNITED STATES)
Trial IDNIH-10674850 on ClinicalTrials.gov

What this research studies

The Health Aging & Later-Life Outcomes Planning (HALLO-P) focuses on understanding how caloric restriction and time-restricted feeding can impact health outcomes in older adults. This research involves a multi-site, randomized clinical trial that will compare the health effects of these dietary interventions against a control group. The study aims to enroll older adults aged 60 and above, utilizing mobile health tools to enhance participant adherence and gather data on the feasibility of the interventions. The goal is to determine whether these dietary strategies can effectively reduce disease and disability risks in this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults aged 60 and above, particularly those with a BMI of 27 kg/m2 or higher.

Not a fit: Patients who are younger than 60 years or have a BMI below 27 kg/m2 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved dietary strategies that enhance health and reduce disease risk in older adults.

How similar studies have performed: Previous clinical trials on caloric restriction have shown beneficial physiological changes, suggesting that this approach may be effective, but the specific outcomes of this trial are yet to be tested.

Where this research is happening

WINSTON-SALEM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.