Investigating the effects of brain stimulation on memory in older adults with mild cognitive impairment
Official title: A Mechanistic Study to Investigate tDCS and Working Memory in MCI Patients
Funded at University of Florida · NIH-11054782 · Data updated 2026-11-12
This study is looking at how a special type of brain stimulation called tDCS might help improve memory for people with mild cognitive impairment, and it’s designed to see how this treatment can make everyday tasks easier.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | December 9, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $147,933 |
| NIH project number | 1K25AG086592-01A1 |
| Project ID | NIH-11054782 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults diagnosed with mild cognitive impairment who are experiencing difficulties with memory.
✕Less likely to help
Patients with severe cognitive impairment or those not diagnosed with mild cognitive impairment may not benefit from this research.
What this research studies
This research focuses on understanding how a specific type of brain stimulation, known as transcranial direct current stimulation (tDCS), can improve working memory in individuals with mild cognitive impairment (MCI). The study aims to explore the neurobiological effects of this stimulation on cognitive functions and how it may enhance daily living activities. Participants will receive a one-time application of tDCS while their brain activity is monitored, allowing researchers to analyze the impact on memory performance and brain connectivity. The research is part of a broader training program for a new investigator in the field of aging and dementia.
Why it matters
Potential benefit: If successful, this research could lead to new non-invasive treatments that improve memory and daily functioning for patients with mild cognitive impairment.
How similar studies have gone: Previous research has shown promising results with tDCS in enhancing cognitive functions, suggesting potential for success in this approach.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Queen, Aprinda Indahlastari — University of Florida
- Study coordinator: Queen, Aprinda Indahlastari
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.