Investigating the effects of Aspergillus fungi in cystic fibrosis patients

The impact of Aspergillus species in cystic fibrosis

NIH-funded research University of Pennsylvania · NIH-10653149

This study is looking at how a type of fungus called Aspergillus affects people with cystic fibrosis, and it aims to help improve their care by understanding the risks and impacts of this fungus on their health and daily life.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10653149 on NIH RePORTER

What this research studies

This research focuses on understanding how Aspergillus species, a type of fungus, affect individuals with cystic fibrosis (CF). The project involves a five-year plan where researchers will collect and analyze respiratory samples from children and adults with CF at the Children's Hospital of Philadelphia and the University of Pennsylvania. By identifying risk factors for Aspergillus isolation and studying its impact on quality of life and treatment outcomes, the research aims to fill critical knowledge gaps in managing fungal infections in CF patients.

Who could benefit from this research

Good fit: Ideal candidates for this research include children and adults diagnosed with cystic fibrosis.

Not a fit: Patients without cystic fibrosis or those who do not have Aspergillus infections may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies and better quality of life for cystic fibrosis patients affected by fungal infections.

How similar studies have performed: Previous research has shown promising results in understanding fungal infections in cystic fibrosis, indicating that this approach could yield valuable insights.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.