Investigating the effects of antihypertensive medications on patient health
High-throughput screening for antihypertensive prescribing cascades
This study is looking at how blood pressure medications can sometimes cause unexpected side effects that lead to more prescriptions, especially in older adults, and aims to find ways to improve how these medications are managed for better health outcomes.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10682502 on NIH RePORTER |
What this research studies
This research focuses on understanding how antihypertensive medications, commonly prescribed to manage high blood pressure, can lead to unintended side effects that may complicate treatment. By employing a novel high-throughput screening method, the study aims to identify and analyze prescribing cascades—situations where additional medications are prescribed to address side effects caused by antihypertensives. This approach seeks to uncover less obvious adverse events that are often overlooked, particularly in older adults, to improve medication management and patient outcomes. The research will utilize large datasets to comprehensively assess these prescribing patterns and their implications for patient care.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are currently prescribed antihypertensive medications.
Not a fit: Patients who are not taking antihypertensive medications or are under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved medication management for patients with hypertension, reducing unnecessary prescriptions and enhancing overall quality of life.
How similar studies have performed: Previous research has shown that understanding prescribing cascades can lead to better patient outcomes, indicating that this approach has potential for success.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Smith, Steven Michael — University of Florida
- Study coordinator: Smith, Steven Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.