Investigating the effects of anesthesia on brain development in young children
Neuroimaging Studies in Pediatric Anesthesia Neurotoxicity
This study is looking at how being put under general anesthesia at a young age might affect learning and behavior in children, and it's for parents who want to understand any potential long-term effects on their little ones' brain development.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10558691 on NIH RePORTER |
What this research studies
This research examines how exposure to general anesthesia in young children may lead to neurodegenerative changes that affect their learning and behavior. By analyzing data from a large cohort of children who underwent anesthesia before the age of three, the study aims to identify specific cognitive deficits and behavioral issues associated with such exposure. Advanced neuroimaging techniques will be employed to assess brain structure and function in these children, providing insights into the long-term impacts of anesthesia on brain development.
Who could benefit from this research
Good fit: Ideal candidates for this research include children under the age of three who have undergone multiple exposures to general anesthesia.
Not a fit: Patients who have not been exposed to general anesthesia or are older than three years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved guidelines for the use of anesthesia in young children, potentially reducing the risk of neurodevelopmental issues.
How similar studies have performed: Previous studies have indicated potential neurodevelopmental risks associated with anesthesia in young children, suggesting that this research builds on established findings.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Warner, David O. — Mayo Clinic Rochester
- Study coordinator: Warner, David O.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.