Investigating the effects of alcohol use and multiple medications in people aging with HIV
The HIV and Alcohol Research center focused on Polypharmacy (HARP)
This study is looking to create personalized treatment plans for older adults living with HIV who might be at risk because of drinking too much alcohol and taking several medications, aiming to find better ways to help them stay healthy.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10906187 on NIH RePORTER |
What this research studies
This research focuses on developing personalized interventions for individuals aging with HIV who are at risk of medical harm due to unhealthy alcohol use and taking multiple medications. By analyzing large-scale electronic health record data from the Veterans Healthcare Administration, the study aims to understand the relationship between alcohol consumption, polypharmacy, and adverse health outcomes. The research includes exploring genetic factors and using biomarkers to assess alcohol use, as well as identifying potential medications for treating alcohol use disorder in the context of polypharmacy. The goal is to create effective treatment strategies that consider the complexities of aging, alcohol use, and multiple medications.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults living with HIV who are experiencing issues related to alcohol use and are taking five or more medications.
Not a fit: Patients who do not have HIV or those who do not consume alcohol may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and health outcomes for older adults living with HIV who struggle with alcohol use and polypharmacy.
How similar studies have performed: Previous research has shown promising results in addressing alcohol use and polypharmacy in similar populations, indicating that this approach has potential for success.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Justice, Amy Caroline — Yale University
- Study coordinator: Justice, Amy Caroline
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.