Investigating the effects of aging and medications on brain health in adults with HIV
Aging, Polypharmacy and Neurotoxicity in Adults Living with HIV
This study is looking at how getting older and taking certain medications might impact brain health in adults with HIV, and it wants to learn more about how these factors can lead to memory problems and mood changes, so if you're living with HIV, you might be invited to share your experiences through some simple assessments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Buffalo NIH-funded |
| Lab location | 1 site (Amherst, United States) |
| Project ID | NIH-10783005 on NIH RePORTER |
What this research studies
This research focuses on understanding how aging and the use of certain medications affect brain health in adults living with HIV. It aims to explore the relationship between cognitive impairments, mood disorders, and the neurotoxic effects of prescribed drugs, particularly antiretroviral therapy. By analyzing data from nearly 20,000 medical assessments collected over two decades, the study seeks to identify how these factors contribute to cognitive decline and depression in older adults with HIV. Patients may be asked to participate in assessments that evaluate their cognitive function and medication use.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults living with HIV who are experiencing cognitive or mood-related issues.
Not a fit: Patients who are not living with HIV or those who are younger than 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that enhance cognitive health and quality of life for older adults living with HIV.
How similar studies have performed: Previous research has shown that understanding the interactions between aging, HIV, and medication effects can lead to significant insights, although this specific approach is relatively novel.
Where this research is happening
Amherst, United States
- State University of New York at Buffalo — Amherst, United States (Active)
Researchers
- Principal investigator: Ma, Qing — State University of New York at Buffalo
- Study coordinator: Ma, Qing
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.