Investigating the effects of a milk protein on infant gut health and immunity
Official title: Evaluation of recombinant bovine lactoferrin and N-linked glycan effects on infant gut health and immunity
Funded at Turtletree Labs INC. · NIH-10821138 · Data updated 2026-11-12
This study is looking at ways to make infant formula healthier by adding a special protein found in breast milk that helps babies' tummies and immune systems, using a new method that’s better for the environment, so that more babies can benefit from safer and more nutritious formula.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Turtletree Labs INC. NIH-funded |
| Lab location | 1 site (Woodland, United States) |
| Project start | September 19, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $311,323 |
| NIH project number | 1R41HD114267-01 |
| Project ID | NIH-10821138 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are infants who are currently being fed formula and may benefit from enhanced nutritional support.
✕Less likely to help
Infants who are exclusively breastfed or those with specific allergies to bovine proteins may not receive benefit from this research.
What this research studies
This research focuses on improving infant formula by incorporating recombinant bovine lactoferrin, a vital protein found in breast milk that supports gut health and immune function. The study utilizes precision fermentation technology to produce this protein, making it more accessible and environmentally sustainable compared to traditional methods. By examining how the glycosylation profile of this protein affects its functionality, the research aims to enhance the nutritional quality of infant formula for better health outcomes in infants. If successful, this could lead to safer and more effective feeding options for infants who rely on formula.
Why it matters
Potential benefit: If successful, this research could significantly improve the health and immunity of infants who are fed formula by providing essential bioactive proteins.
How similar studies have gone: Previous research has shown promise in using bioactive proteins to enhance infant nutrition, indicating that this approach could be effective.
Where this research is happening
-
Turtletree Labs INC.
Woodland, United States Active
Researchers
- Principal investigator: Feher Castagna, Vanessa Patricia — Turtletree Labs INC.
- Study coordinator: Feher Castagna, Vanessa Patricia
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.