Investigating the effects of a common pesticide on ovarian health
Toxicity and Detoxification of Imidacloprid in the Murine Ovary
This study is looking at how a common pesticide called imidacloprid might affect the reproductive health of animals by examining changes in their ovaries, which could help us understand the risks it poses to both animals and humans.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Urbana-Champaign NIH-funded |
| Lab location | 1 site (Champaign, United States) |
| Project ID | NIH-10907831 on NIH RePORTER |
What this research studies
This research focuses on understanding how imidacloprid, a widely used neonicotinoid pesticide, affects the ovaries of non-target species, particularly in terms of reproductive health. The study will explore the mechanisms of toxicity, specifically how imidacloprid and its metabolites interact with acetylcholine pathways in ovarian cells. By examining the morphological changes in ovarian follicles and hormonal alterations, the research aims to uncover the potential risks associated with chronic exposure to this pesticide. The findings could provide insights into the broader implications for human and animal health due to pesticide exposure.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with concerns about pesticide exposure and its effects on reproductive health.
Not a fit: Patients who are not affected by pesticide exposure or do not have reproductive health concerns may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved safety regulations regarding pesticide use, ultimately protecting reproductive health in humans and wildlife.
How similar studies have performed: While there is limited research specifically on imidacloprid's effects on ovarian health, studies on other neonicotinoids have indicated potential reproductive toxicity, suggesting that this area of investigation is both relevant and necessary.
Where this research is happening
Champaign, United States
- University of Illinois at Urbana-Champaign — Champaign, United States (Active)
Researchers
- Principal investigator: Mourikes, Vasiliki — University of Illinois at Urbana-Champaign
- Study coordinator: Mourikes, Vasiliki
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.