Investigating the effectiveness of combining local therapy with standard treatment for recurrent prostate cancer in veterans
Veterans Affairs seamless phase II/III randomized trial of STAndard systemic theRapy with or without PET-directed local therapy for OligoRecurrenT prostate cancer (VA STARPORT)
['FUNDING_OTHER'] · EDWARD HINES JR VA HOSPITAL · NIH-11073061
This study is looking at veterans with recurrent prostate cancer that has spread to a few places in the body, and it wants to see if adding local treatments like surgery or radiation to their usual hormone therapy can help them live longer and feel better.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | EDWARD HINES JR VA HOSPITAL (nih funded) |
| Locations | 1 site (HINES, UNITED STATES) |
| Trial ID | NIH-11073061 on ClinicalTrials.gov |
What this research studies
This research focuses on veterans with recurrent prostate cancer, specifically those with oligorecurrent disease, which means they have 1-5 sites of metastases. The study aims to evaluate whether adding local therapy, such as surgery or radiation, to standard systemic hormonal therapy can improve patient outcomes. By comparing the effectiveness of this combined approach against standard treatment alone, the research seeks to determine if it can lead to better disease control and potentially longer survival. Participants will be closely monitored for progression-free survival and overall health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans diagnosed with oligorecurrent prostate cancer who have undergone initial local therapy and are experiencing recurrence.
Not a fit: Patients with advanced metastatic prostate cancer involving multiple sites or those who have not received prior local therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide veterans with a more effective treatment option that may improve survival rates and quality of life.
How similar studies have performed: Previous studies have shown promising results with metastasis-directed therapy in similar patient populations, indicating potential for success in this approach.
Where this research is happening
HINES, UNITED STATES
- EDWARD HINES JR VA HOSPITAL — HINES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SOLANKI, ABHISHEK ASHOK — EDWARD HINES JR VA HOSPITAL
- Study coordinator: SOLANKI, ABHISHEK ASHOK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Best Disease, Cancer Cause, Cancer Control, Cancer Control Science, cancer diagnosis