Investigating the early signs of Alzheimer's disease and related dementias.
NAPS2 Clinical Core
This study is looking for people with REM Sleep Behavior Disorder to help us learn more about the early signs of Alzheimer's and related dementias, so we can find ways to delay or prevent these conditions in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10866369 on NIH RePORTER |
What this research studies
This research focuses on understanding the early stages of Alzheimer's disease and related dementias by collecting extensive clinical and biomarker data from participants diagnosed with REM Sleep Behavior Disorder (RBD). Patients will undergo various assessments, including blood tests, brain imaging, and neurocognitive evaluations, to identify potential markers of disease progression. The goal is to gather valuable information that can help develop therapies aimed at delaying or preventing the onset of more severe forms of dementia. Participants will contribute to a larger international consortium, enhancing the overall understanding of these conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with REM Sleep Behavior Disorder (RBD) who may be at risk for developing Alzheimer's disease or related dementias.
Not a fit: Patients who do not have REM Sleep Behavior Disorder or those with advanced stages of Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that delay or prevent the progression of Alzheimer's disease and related dementias.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for Alzheimer's disease and related dementias, suggesting that this approach could yield valuable insights.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Boeve, Bradley F — Washington University
- Study coordinator: Boeve, Bradley F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.