Investigating the diversity of Candida auris strains in hospitals
Official title: Within-patient Candida auris strain diversity in a tertiary hospital
Funded at University of Pittsburgh at Pittsburgh · NIH-10906966 · Data updated 2026-11-12
This study is looking at the different types of a fungus called Candida auris that can cause serious infections, especially in hospitals, to find out how they respond to treatments and how they make people sick, which could help doctors find better ways to treat patients.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | August 14, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $198,750 |
| NIH project number | 5R21AI178695-02 |
| Project ID | NIH-10906966 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who have been diagnosed with Candida auris infections or are at high risk for such infections.
✕Less likely to help
Patients with infections caused by other types of fungi or those not at risk for Candida auris may not benefit from this research.
What this research studies
This research focuses on understanding the genetic diversity of Candida auris, a fungus that causes serious infections and is known for its resistance to antifungal treatments. By examining different strains of C. auris found in a hospital setting, the study aims to uncover how these strains vary in their susceptibility to drugs and their ability to cause disease. Patients may benefit from this research as it could lead to improved treatment strategies and better management of infections caused by this pathogen.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for infections caused by Candida auris, potentially reducing mortality rates.
How similar studies have gone: Other research has shown success in understanding genetic diversity in fungal pathogens, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Nguyen, M. Hong Thi — University of Pittsburgh at Pittsburgh
- Study coordinator: Nguyen, M. Hong Thi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.