Investigating the development of chronic fatigue syndrome after infectious mononucleosis
Official title: Maintenance and Incidence of ME/CFS following Mono
Funded at De Paul University · NIH-10745993 · Data updated 2026-11-12
This study is looking at how different mental and physical factors might lead to chronic fatigue syndrome after someone has infectious mononucleosis, and it’s for college students who want to help researchers understand why some people get tired and stay that way while others recover.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | De Paul University NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | January 1, 2020 |
| Project end | November 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $548,229 |
| NIH project number | 5R01NS111105-05 |
| Project ID | NIH-10745993 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are young adults, particularly college students, who have experienced infectious mononucleosis.
✕Less likely to help
Patients who have not had infectious mononucleosis or are outside the young adult age range may not benefit from this research.
What this research studies
This research focuses on understanding how certain psychological and biological factors may contribute to the development of chronic fatigue syndrome (ME/CFS) following infectious mononucleosis (IM). The study involves tracking a diverse group of college students over time, collecting health and psychological data before, during, and after their illness. By comparing those who develop ME/CFS with those who recover, researchers aim to identify key predictors and maintenance factors for this condition. Participants will be monitored for several years to gather comprehensive data on their health outcomes.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of ME/CFS, potentially improving treatment options for affected individuals.
How similar studies have gone: While there have been studies on ME/CFS, this research takes a novel approach by following subjects from before the onset of IM, which has not been extensively explored.
Where this research is happening
-
De Paul University
Chicago, United States Active
Researchers
- Principal investigator: Jason, Leonard a — De Paul University
- Study coordinator: Jason, Leonard a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.