Investigating the dental risks of medications used for opioid addiction treatment
Official title: Comparative Risk of Oral Complications Associated with Medications for Opioid Use Disorder: A Mixed-Methods Approach
Funded at University of Pittsburgh at Pittsburgh · NIH-10765049 · Data updated 2026-11-12
This study is looking into how medications for treating opioid addiction, especially buprenorphine, might affect your dental health, so we can better understand the risks and benefits for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | September 21, 2023 |
| Project end | September 20, 2025 |
| Funding year | 2023 |
| Award (this year) | $1,275,122 |
| NIH project number | 1R01DE033322-01 |
| Project ID | NIH-10765049 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals currently receiving or considering medications for opioid use disorder, particularly those using buprenorphine.
✕Less likely to help
Patients who are not using or considering medications for opioid use disorder may not benefit from this research.
What this research studies
This research examines the potential oral health complications associated with medications used to treat opioid use disorder (OUD), particularly focusing on buprenorphine. By gathering data through observational studies and interviews with patients and healthcare providers, the project aims to clarify the relationship between these medications and dental issues. The findings will help inform both patients and providers about the risks and benefits of these treatments, ultimately aiming to improve patient care and decision-making regarding opioid addiction therapies.
Why it matters
Potential benefit: If successful, this research could provide critical evidence to help patients and healthcare providers make informed decisions about opioid use disorder treatments and their potential impact on dental health.
How similar studies have gone: While there have been discussions and preliminary reports regarding the dental risks of opioid use disorder medications, this research aims to fill a significant gap in rigorous evidence, making it a novel approach.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Roy, Payel Jhoom — University of Pittsburgh at Pittsburgh
- Study coordinator: Roy, Payel Jhoom
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.