Investigating the connection between menopause symptoms and heart disease in women
Official title: Vasomotor symptoms of menopause and cardiovascular disease: What is the link?
Funded at University of Minnesota · NIH-10910162 · Data updated 2026-11-12
This study is looking at how hot flashes and night sweats during menopause might affect heart health in women, helping us understand why these symptoms could lead to a higher risk of heart disease.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | September 1, 2023 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $192,643 |
| NIH project number | 5R21AG080503-02 |
| Project ID | NIH-10910162 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are menopausal women experiencing vasomotor symptoms.
✕Less likely to help
Patients who are not menopausal or do not experience vasomotor symptoms may not benefit from this research.
What this research studies
This research focuses on understanding how vasomotor symptoms (VMS), such as hot flushes and night sweats, affect the risk of cardiovascular disease (CVD) in menopausal women. The study aims to identify the mechanisms that link these symptoms to cardiovascular health by examining autonomic and vascular function in women experiencing VMS. By analyzing these factors, the research seeks to clarify how hot flushes may influence heart health and contribute to the higher risk of CVD in this population.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing cardiovascular disease in menopausal women.
How similar studies have gone: Previous research has indicated a link between menopausal symptoms and cardiovascular health, suggesting that this investigation could build on established findings.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Keller-Ross, Manda Linea — University of Minnesota
- Study coordinator: Keller-Ross, Manda Linea
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.