Investigating the connection between gut health and liver disease in people with HIV
The Gut-Liver Axis in HIV-Related Non-Alcoholic Fatty Liver Disease
This study is looking at how the bacteria in your gut and your overall gut health might influence liver disease, especially non-alcoholic fatty liver disease (NAFLD), in people living with HIV, to help find new ways to spot and treat liver issues early.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11097290 on NIH RePORTER |
What this research studies
This research explores how the gut microbiome and intestinal health affect liver disease, specifically non-alcoholic fatty liver disease (NAFLD), in individuals living with HIV. The study will analyze the differences in gut bacteria and metabolites in patients with HIV and NAFLD compared to those without liver disease. By examining these factors, the research aims to uncover the mechanisms that contribute to liver disease in this population and identify potential biomarkers for early detection and treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are experiencing or at risk for non-alcoholic fatty liver disease.
Not a fit: Patients who do not have HIV or those without liver disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of liver disease in people living with HIV.
How similar studies have performed: Previous research has indicated that gut health plays a significant role in liver disease, suggesting that this approach could yield valuable insights.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Gabriel, Curtis Lee — Vanderbilt University Medical Center
- Study coordinator: Gabriel, Curtis Lee
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.