Investigating the characteristics of a common strain of C. difficile bacteria
Epidemiological and Genomic Characteristics of the Widely Disseminated C. difficile Strain, REA Group Y
['FUNDING_OTHER'] · VA SALT LAKE CITY HEALTHCARE SYSTEM · NIH-10950314
This study is looking at a specific strain of C. difficile that’s been causing more infections in the community, and it aims to understand its characteristics and how we can better prevent these infections.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VA SALT LAKE CITY HEALTHCARE SYSTEM (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-10950314 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the epidemiological and genomic features of the C. difficile strain known as REA group Y, which has been increasingly associated with community-acquired infections. The study aims to analyze the molecular characteristics of this strain and its clinical implications, particularly as it relates to rising infection rates in the community. By employing advanced genomic sequencing techniques, researchers will gather detailed data on the strain's prevalence and its potential reservoirs in the community. This comprehensive analysis could provide insights into how to better manage and prevent C. difficile infections.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced C. difficile infections, particularly those with community-acquired cases.
Not a fit: Patients who have never had a C. difficile infection or those with infections caused by strains other than REA group Y may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating C. difficile infections, ultimately reducing infection rates and associated healthcare costs.
How similar studies have performed: While there has been significant research on C. difficile, this specific focus on the REA group Y strain represents a novel approach that has not been extensively studied before.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- VA SALT LAKE CITY HEALTHCARE SYSTEM — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SKINNER, ANDREW MICHAEL — VA SALT LAKE CITY HEALTHCARE SYSTEM
- Study coordinator: SKINNER, ANDREW MICHAEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.