Investigating the causes of health disparities in inflammatory breast cancer among African American women
Molecular Determinants of Health Disparities in Inflammatory Breast Cancer
This study is looking into why inflammatory breast cancer is tougher and more common in African American women than in white women, and it hopes to find ways to improve treatment and survival by exploring factors like health history and weight.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10914856 on NIH RePORTER |
What this research studies
This research focuses on understanding why inflammatory breast cancer (IBC) is more aggressive and prevalent in African American women compared to white women. It aims to identify the biological mechanisms that contribute to these disparities and explore how modifiable risk factors, such as reproductive history and body mass index, affect treatment outcomes. By examining the adaptive stress response in IBC cells, the study seeks to uncover potential therapeutic targets that could improve survival rates for affected patients. The research combines epidemiological studies with laboratory analyses to provide a comprehensive view of the issue.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American women diagnosed with inflammatory breast cancer.
Not a fit: Patients who do not have inflammatory breast cancer or those outside the African American demographic may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and outcomes for African American women diagnosed with inflammatory breast cancer.
How similar studies have performed: While there has been research on breast cancer disparities, this study's specific focus on the biological mechanisms in inflammatory breast cancer among African American women is relatively novel.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Devi, Gayathri — Duke University
- Study coordinator: Devi, Gayathri
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.