Investigating the causes of congenital obstructive uropathy and its variations
Human genetic studies to solve the etiology of congenital obstructive uropathy and its subphenotypes
This study is looking at the genetic causes of kidney and urinary tract problems, especially congenital obstructive uropathy, to help improve care and support for families affected by these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11144684 on NIH RePORTER |
What this research studies
This research focuses on congenital anomalies of the kidney and urinary tract, particularly congenital obstructive uropathy (COU), which can lead to severe health issues in affected individuals. The study aims to identify genetic factors contributing to these conditions, enhancing our understanding of their etiology. By utilizing advanced genetic testing and analysis, the research seeks to improve prenatal care, risk assessment, and management strategies for families impacted by COU. Ultimately, the goal is to provide better prognostic information and support for patients and their families.
Who could benefit from this research
Good fit: Ideal candidates for this research include expectant parents whose fetuses have been diagnosed with congenital obstructive uropathy or related kidney anomalies.
Not a fit: Patients with congenital kidney anomalies that are not obstructive in nature may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prenatal care and management strategies for families affected by congenital obstructive uropathy.
How similar studies have performed: Previous research has shown promise in understanding genetic factors related to congenital anomalies, suggesting potential for success in this area as well.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Sanna-Cherchi, Simone — Columbia University Health Sciences
- Study coordinator: Sanna-Cherchi, Simone
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.