Investigating the causes of aortic stenosis using advanced imaging techniques
Advanced Non-invasive Imaging in the Investigation of Aortic Stenosis Pathobiology
This study is looking at aortic stenosis, a heart valve condition that often affects older adults, to better understand how it develops and to find new ways to treat it, which could help improve care for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-10892832 on NIH RePORTER |
What this research studies
This research focuses on understanding aortic stenosis, a condition that affects many elderly individuals, by utilizing advanced non-invasive imaging methods. The study aims to explore the biological processes that lead to the disease, particularly how certain cells in the heart valve change and contribute to the condition. By examining these changes in detail, the researchers hope to identify potential new treatments that could slow the progression of aortic stenosis. Patients may benefit from improved diagnostic techniques and future therapies that arise from this research.
Who could benefit from this research
Good fit: Ideal candidates for this research are elderly individuals aged 65 and older who are diagnosed with or at risk for aortic stenosis.
Not a fit: Patients who are younger than 65 or do not have aortic stenosis may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that slow the progression of aortic stenosis, improving outcomes for patients.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to study heart conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Lindner, Jonathan R — University of Virginia
- Study coordinator: Lindner, Jonathan R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.