Investigating the causes of alcoholic ketoacidosis in mice
Official title: Study of alcoholic ketoacidosis in mice
Funded at Emory University · NIH-11060880 · Data updated 2026-11-12
This study is looking at how alcoholic ketoacidosis happens in people who drink a lot of alcohol and don’t eat well, using mice to learn more about the problem so we can find better ways to help those affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | April 1, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $349,770 |
| NIH project number | 5R01AA030893-02 |
| Project ID | NIH-11060880 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with a history of chronic alcohol use who may be at risk for developing alcoholic ketoacidosis.
✕Less likely to help
Patients who do not consume alcohol or have no history of alcohol-related health issues are unlikely to benefit from this research.
What this research studies
This research focuses on understanding alcoholic ketoacidosis, a serious metabolic condition resulting from chronic alcohol consumption and poor nutrition. By studying mice that have been induced with this condition, researchers aim to uncover the underlying mechanisms that lead to metabolic acidosis, characterized by low blood bicarbonate levels and high ketone bodies. The approach involves modifying alcohol feeding protocols to replicate the condition in a controlled environment, allowing for detailed observation and analysis. Insights gained from this research could inform future strategies to prevent and manage this dangerous condition in humans.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for alcoholic ketoacidosis, potentially saving lives.
How similar studies have gone: While there has been limited research on alcoholic ketoacidosis, preliminary studies in animal models have shown promise in understanding its mechanisms.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Choi, Inyeong — Emory University
- Study coordinator: Choi, Inyeong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.