Investigating the causes and solutions for Type 2 diabetes in young people
Official title: Understanding and Targeting the Pathophysiology of Youth-onset Type 2 Diabetes
Funded at Arizona State University-Tempe Campus · NIH-11051228 · Data updated 2026-11-12
This study is looking at what causes Type 2 diabetes in young people, especially those from low-income and minority backgrounds, and it aims to find ways to help prevent and manage the condition by working closely with the community to create solutions that fit their needs.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Arizona State University-Tempe Campus NIH-funded |
| Lab location | 1 site (Tempe, United States) |
| Project start | March 10, 2023 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $662,069 |
| NIH project number | 5U01DK134978-03 |
| Project ID | NIH-11051228 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include youth aged 0-20 years, particularly those from low-income or minority backgrounds who are at risk for Type 2 diabetes.
✕Less likely to help
Patients who do not fall within the youth age range or those without risk factors for Type 2 diabetes may not benefit from this research.
What this research studies
This research focuses on understanding the complex factors contributing to Type 2 diabetes (T2D) in youth, particularly among low-income and minority populations. It examines biological, social, and environmental influences that lead to disparities in T2D. The study employs a transdisciplinary approach, integrating insights from various fields to develop effective prevention and management strategies. By engaging with community members, the research aims to create culturally relevant interventions that address the unique challenges faced by at-risk youth.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and management strategies for Type 2 diabetes in young people, enhancing their quality of life.
How similar studies have gone: Previous research has shown success in addressing health disparities in diabetes through community-engaged approaches, indicating potential for this study's methods.
Where this research is happening
-
Arizona State University-Tempe Campus
Tempe, United States Active
Researchers
- Principal investigator: Shaibi, Gabriel Quantum — Arizona State University-Tempe Campus
- Study coordinator: Shaibi, Gabriel Quantum
Related research
Other NIH-funded projects on the same topics.
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Subtyping Core for Research on the Causes of Type 2 Diabetes (SCORE-T2D)
A new U01 grant from a university research team aims to understand why Type 2 diabetes differs so much between people and how to tailor prevention and treatment.
-
Michigan Diabetes Project: A Peer-Led Self-Management Program for Adults with Type 2 Diabetes
A peer-led self-management program for adults with type 2 diabetes is being tested to see if it improves blood sugar control and daily diabetes care.
-
Alzheimer’s and dementia risk in people with prediabetes or type 2 diabetes
This grant aims to understand why some older adults with prediabetes or type 2 diabetes develop memory problems or dementia.
-
Personalized use of newer diabetes medicines for Type 2 diabetes
Aiming to tailor use of newer glucose-lowering drugs for people with type 2 diabetes to improve health and access in real-world settings.
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Alzheimer’s and related dementia in older adults with prediabetes or type 2 diabetes
This grant aims to understand why cognitive problems occur in people 65 and older who have prediabetes or type 2 diabetes, using data from a long-running diabetes study to identify what drives memory and thinking decline.
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Understanding why youth develop type 2 diabetes and how to prevent it
A nationwide study aims to unravel why some teens with obesity develop type 2 diabetes while others don’t, and to identify factors that could help prevent it.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.