Investigating the causes and risks of complex diseases using genomic data
Resolving Methodological Challenges in Genomics Research: Causality, Risk Prediction, and Reproducibility
['FUNDING_OTHER'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-10898006
This study is looking at how certain diseases are connected to changes in our genes, and it's creating easy-to-use tools for researchers to help them understand these links better and predict health risks.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-10898006 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the causal relationships between complex diseases and their molecular mechanisms using advanced genomic technologies. By developing new computational methods, the project aims to analyze observational data to infer causality and predict risks associated with various diseases. Additionally, it will create user-friendly software tools that will be accessible to researchers in the biological and medical fields, enhancing their ability to conduct reproducible experiments and analyses.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with complex diseases or those at risk of developing such conditions, particularly those who may benefit from genomic insights.
Not a fit: Patients with conditions that are not influenced by genetic factors or those who do not have access to genomic testing may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for predicting disease risk and understanding disease mechanisms, ultimately benefiting patient care and preventive medicine.
How similar studies have performed: Previous research has shown success in using computational methods for causal inference in genomics, indicating that this approach has potential for significant advancements.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WEN, XIAOQUAN — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: WEN, XIAOQUAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.