Investigating the causes and risk factors of persistent tinnitus
A Multi-omics Investigation of Incident Persistent Tinnitus
This study is looking for answers about what causes ongoing tinnitus, which affects more than 50 million people in the U.S., by examining biological and genetic factors in a large group of participants, with the hope of finding better treatments and ways to prevent it.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10892938 on NIH RePORTER |
What this research studies
This research aims to understand the underlying causes of persistent tinnitus, a condition affecting over 50 million Americans. By analyzing biological markers and genetic factors in large groups of individuals, the study seeks to identify risk factors that contribute to the development of tinnitus. Participants will be involved in collecting data that may reveal how environmental exposures and genetic predispositions influence tinnitus. The ultimate goal is to improve treatment options and preventative strategies for those suffering from this debilitating condition.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing persistent tinnitus or those at risk of developing it, particularly women and younger, diverse populations.
Not a fit: Patients who do not experience tinnitus or have no risk factors for developing the condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management and treatment options for individuals suffering from persistent tinnitus.
How similar studies have performed: Other research has shown promise in identifying risk factors for tinnitus, but this multi-omics approach is relatively novel and aims to expand the understanding of the condition significantly.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Zeleznik, Oana Alina — Brigham and Women's Hospital
- Study coordinator: Zeleznik, Oana Alina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.