Investigating the causes and prevention of youth-onset type 2 diabetes.
Understanding and Targeting the Pathophysiology of Youth-onset Type 2 Diabetes-Texas Children's Center.
This study is looking at what causes type 2 diabetes in kids aged 8 to 14, especially those who seem healthy but might be at risk, so we can find ways to prevent it from developing.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11042828 on NIH RePORTER |
What this research studies
This research focuses on understanding the complex factors that lead to youth-onset type 2 diabetes (T2D), which progresses more rapidly than adult-onset diabetes. The study aims to identify high-risk children aged 8 to 14 years who have normal glucose tolerance or prediabetes, and to monitor their health over time. By collaborating with various clinical centers, the researchers will conduct in-depth assessments and surveys to explore how hormonal and environmental factors contribute to the development of T2D. The goal is to uncover the risk factors and biological changes that can help prevent this condition in young individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 8 to 14 years who are at high risk for developing type 2 diabetes, particularly those with normal glucose tolerance or prediabetes.
Not a fit: Patients who are older than 14 years or those who already have a diagnosis of type 2 diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to effective prevention strategies for youth-onset type 2 diabetes, reducing the risk of serious health complications in children.
How similar studies have performed: Previous research has shown promising results in understanding and preventing adult-onset diabetes, but this specific focus on youth-onset type 2 diabetes is relatively novel.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Bacha, Fida — Baylor College of Medicine
- Study coordinator: Bacha, Fida
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.