Investigating the causes and prevention of youth-onset type 2 diabetes
Understanding and Targeting the Pathophysiology of Youth-onset Type 2 Diabetes - Biostatistics Research Center
This study is looking at why some young people develop type 2 diabetes during puberty while others stay healthy, hoping to find ways to prevent and treat the condition better for kids and teens.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | George Washington University NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project ID | NIH-11042216 on NIH RePORTER |
What this research studies
This research focuses on understanding the factors that contribute to the development of type 2 diabetes in young people, particularly during puberty when insulin sensitivity changes. It aims to identify why some adolescents maintain healthy insulin function while others do not, despite having similar characteristics. By examining the progression from normal blood sugar levels to prediabetes and then to diabetes, the study will explore the impact of various risk factors, including environmental influences and differences based on sex and ethnicity. The findings could lead to better prevention and treatment strategies tailored for youth.
Who could benefit from this research
Good fit: Ideal candidates for this research include adolescents and young adults who are at risk for or currently experiencing youth-onset type 2 diabetes.
Not a fit: Patients who are not within the youth age range or those with adult-onset type 2 diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for youth-onset type 2 diabetes, ultimately reducing its prevalence and impact on young individuals.
How similar studies have performed: Previous research has shown promise in understanding diabetes risk factors in youth, but this study aims to provide a more comprehensive and targeted approach, making it a novel effort in this area.
Where this research is happening
Washington, United States
- George Washington University — Washington, United States (Active)
Researchers
- Principal investigator: Braffett, Barbara Halina — George Washington University
- Study coordinator: Braffett, Barbara Halina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.