Investigating the causes and potential treatments for cancer cachexia
CANCAN - PENNINGTON
['FUNDING_OTHER'] · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · NIH-10625678
This study is looking into why many cancer patients experience severe weight loss and muscle loss, called cancer cachexia, to help improve their treatment and quality of life.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LSU PENNINGTON BIOMEDICAL RESEARCH CTR (nih funded) |
| Locations | 1 site (BATON ROUGE, UNITED STATES) |
| Trial ID | NIH-10625678 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding cancer cachexia, a serious condition affecting around 80% of cancer patients, characterized by significant weight loss and muscle wasting. The study aims to identify the underlying mechanisms that lead to this debilitating syndrome, which can worsen treatment outcomes and reduce quality of life. By assembling a diverse team of experts, the research will explore how tumors influence metabolic processes and contribute to cachexia. The methodology includes advanced techniques to analyze metabolic interactions in both animal models and clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients experiencing significant weight loss and muscle wasting.
Not a fit: Patients not suffering from cancer or those without symptoms of cachexia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to effective therapies for cancer cachexia, improving treatment responses and quality of life for cancer patients.
How similar studies have performed: While there has been extensive research on cancer cachexia, this approach is novel in its focus on the upstream mediators and systemic interactions involved.
Where this research is happening
BATON ROUGE, UNITED STATES
- LSU PENNINGTON BIOMEDICAL RESEARCH CTR — BATON ROUGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HEYMSFIELD, STEVEN — LSU PENNINGTON BIOMEDICAL RESEARCH CTR
- Study coordinator: HEYMSFIELD, STEVEN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.