Investigating the causes and potential treatments for cancer cachexia.
CANCAN - ROCHESTER
This study is looking into cancer cachexia, a tough condition that affects many cancer patients by causing weight loss and muscle loss, and aims to find out how tumors impact the body’s metabolism so that better treatments can be developed to help patients feel better and respond well to their cancer care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10625145 on NIH RePORTER |
What this research studies
This research focuses on understanding cancer cachexia, a serious condition affecting around 80% of cancer patients, characterized by significant weight loss and muscle wasting. The study aims to identify the underlying mechanisms that lead to this debilitating syndrome, which can worsen treatment outcomes and reduce quality of life. By forming a virtual institute of experts from various fields, the research will utilize advanced techniques to analyze how tumors influence metabolic processes in the body. The goal is to discover effective therapies that could improve patient responses to cancer treatment and enhance overall well-being.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients experiencing significant weight loss and muscle wasting.
Not a fit: Patients who are not currently undergoing cancer treatment or do not exhibit symptoms of cachexia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to effective treatments for cancer cachexia, improving survival rates and quality of life for cancer patients.
How similar studies have performed: While there has been extensive research on cancer cachexia, this approach is novel in its focus on the upstream mediators and host-tumor interactions.
Where this research is happening
Rochester, United States
- University of Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Mustian, Karen M. — University of Rochester
- Study coordinator: Mustian, Karen M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.